Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for ALIROCUMAB. Table 5. Light Gray Zone - Brands that have no equivalent generics available - WILL NOT require patient to try a generic for coverage Dose Conversion Table for Statins: Title: Microsoft Word - Lipids dose conversion chart 5.2.08.doc Author: SchweRJ Created Date: Relevance | Approximate equivalent rosuvastatin doses for temporary statin interchange programs Source: Database of Abstracts of Reviews of Effects - DARE (Add filter) prolonged-release tablet of Dorisin XL contains 84.2mg fluvastatin sodium equivalent to 80mg fluvastatin free acid. MHRA advice: there is an increased risk of myopathy associated with high dose (80 mg) simvastatin. For all patients with an acute coronary syndrome (ACS), we recommend high-intensity statin therapy (atorvastatin 80 mg daily or rosuvastatin 20 or 40 mg… but CABG is usually preferred for the treatment of patients with left main or left main equivalent disease,… › Prescribing and Technical Information (139), All Wales Medicines Strategy Group - AWMSG (2), British and Irish Hypertension Society - BIHS (1), British Association for Psychopharmacology - BAP (1), British Association of Dermatologists - BAD (2), British Society of Gastroenterology - BSG (2), Civitas: Institute for the Study of Civil Society (2), Cochrane Central Register of Controlled Trials (3), Cochrane Database of Systematic Reviews (1), Database of Abstracts of Reviews of Effects - DARE (6), electronic Medicines Compendium - eMC (155), European Association of Urology - EAU (1), European League Against Rheumatism - EULAR (2), European Society for Medical Oncology - ESMO (1), Evidence for Policy and Practice Information and Co-ordinating Centre - EPPI-Centre (1), Faculty of Dental Surgery, Royal College of Surgeons (1), Faculty of Sexual and Reproductive Healthcare (1), Guidelines and Audit Implementation Network - GAIN (1), National Institute for Health and Care Excellence - NICE (23), National Institute for Health Research - NIHR (1), NHS Economic Evaluation Database - NHS EED (7), NIHR Journals Library - Public Health Research (1), Organisation for Economic Cooperation and Development - OECD (1), Royal College of Physicians of London - RCP (2), Scottish Intercollegiate Guidelines Network - SIGN (4), WHO Regional Office for Europe - WHO Europe (12), View options for downloading these results, Lipid modification - CVD prevention: Scenario: Lipid therapy - secondary prevention of CVD, Lipid modification - CVD prevention: Scenario: Lipid therapy - primary prevention of CVD, Alirocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia - guidance (TA393), Heart failure - chronic: Scenario: Confirmed heart failure with preserved ejection fraction, Dorisin XL 80mg Prolonged Release Tablets - Summary of Product Characteristics (SmPC) - (emc). Sort by Date. Click export CSV or RIS to download the entire page or use the checkbox in each result to select a subset of records to download. Statin Dose Intensity and Equivalency Chart* Statin Intensity %LDL-C Reduction HMG-CoA Reductase Inhibitor Rosuvastatin Atorvastatin Pitavastatin Simvastatin Lovastatin Pravastatin Fluvastatin High-Intensity (lowers LDL-C ≥ 50%) 63 40 mg ($196) View options for downloading these results. Dosage adjustment may be needed based on renal function, race, or drug interactions. Showing results 1 to 10. Sorted by . View all similar results. Advise adults to start lipid modification therapy if they have established cardiovascular disease (for example past or current history of myocardial infarction,... Offer lipid modification therapy to people aged 84 years and younger if their estimated 10-year risk of developing cardiovascular disease (CVD) using the QRISK... Evidence-based recommendations on alirocumab (Praluent) for treating primary hypercholesterolaemia (high cholesterol) and mixed dyslipidaemia. The 80 mg dose should be considered only in patients with severe hypercholesterolaemia and high risk of cardiovascular complications who have not achieved their treatment goals on lower doses, when the benefits are expected to outweigh the potential risks. Statin Dose Comparison The chart below shows statin doses expected to provide similar LDL reduction. … maintenance doses cited below. Approximate equivalent rosuvastatin doses for temporary statin interchange programs var _gaq. There are many similar Summary of Product Characteristics from eMC. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for EVOLOCUMAB. When choosing a statin dose, expected LDL reduction is not the only factor to consider. 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